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Nightbreed are divided into four classes:
 
*Alpha - metahumans born with their abilities who have ungergone special gene-therapy to produce the Nightbreed solution in their bodies. [[Kyle Armalin]] is the last of the four ''known'' Alpha Nightbreed.
*Beta - recieve their abilities through blood transfusions or 'mixing' of blood and the Nightbreed activation solution. Betas are generally not subject to any psychological inhibitions on their abilities that Alphas possess. Considered the most powerful of the Nightbreed. Transformation to Beta class is refered to as 'being turned'. [[Franklin Davers]] is a Beta Nightbreed.
*Gamma - recieve their abilities through the Nightbreed solution. Their power levels are typically far less than those of Alphas or Betas, and are limited to physical enhancements of ten to twenty times their pre-boost state. Unlike Alphas or Betas, Gamma Nightbreed cannot produce the Nightbreed solution in their own bodies. Transformation to Gamma class is refered to as 'being sired'.
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